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[Skincare](/beauty/skincare)

 /  22 November 2024  

#  The Skin-Rejuvenating Treatment Everyone’s Talking About  


You might have heard of Polynucleotides – the new, injectable bio-stimulator that is crafted from purified fish DNA fragments that encourage collagen and elastin production. It offers short and long-term improvements in collagen production that deliver smoother, firmer skin over time. Here, Thérapie Clinic’s Dr Farah Kanji explains why there’s so much buzz, the results you can expect and how you can get the treatment for less at any Thérapie Clinic nationwide this Black Friday…  


ByRebecca Hull

  /  

[ Save To My Favourites ](/user/login?destination=/markdownify/node/41818)

 

 

 Created in partnership with Thérapie Clinic



 

 

 

 

## What It Is 



  

“Polynucleotides are chains of ‘nucleotides’ or ‘nucleic acids’, which are the molecular building blocks of DNA and RNA. These compounds are now being used in aesthetic medicine because they are believed to stimulate skin’s fibroblasts, triggering rejuvenation by promoting cell growth and collagen production, and by repairing aged tissue. Polynucleotides used for cosmetic purposes are often harvested from fish sources – that includes salmon sperm. The benefits of these injectable treatments include improved skin hydration, elasticity and smoother texture. They are particularly useful around the eye to reduce the appearance of crepey skin or dark circles. You’ll also find they stimulate the production of new blood vessels and promote wound healing. At [Thérapie](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle), we use a product that combines polynucleotides and hyaluronic acid. The function of the latter helps to draw in water and hold it there, improving skin’s suppleness and moisture levels.”

 

## Why It’s Different 



  

“I’m often asked how Polynucleotides differs to other treatments, like Botox. Polynucleotides stimulate collagen production to rejuvenate skin, while Botox temporarily relaxes muscles to reduce wrinkles, while dermal fillers are used to add volume. It also differs to Profhilo, which is a hyaluronic acid-based product that hydrates skin and stimulates both collagen and elastin production through its unique formulation. The key difference between these treatments lies in their intended outcomes: polynucleotides focus on cellular repair, delivering overall skin improvement with a naturally undetectable, refreshed look."

 

## Where It Works Best 



  

“Polynucleotides work in areas of the skin that many skin boosters, like Profhilo, can’t – think eyes, lips and forehead. The main site that people opt for is the eye area as it’s the first place you see signs of ageing and skin laxity. Polynucleotides can improve the thickness and health of the skin, reducing the appearance of under-eye hollows and dark circles over time. As a treatment, it’s different to anything else, which is why a consultation with a medical practitioner like those at [Thérapie](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle) clinic is so important.”

 

 

 [ ![](https://media.sheerluxe.com/nRRY6xB2DCIf-_7YICH-r6CL31w=/800x0/smart/https%3A%2F%2Fsheerluxe.com%2Fsites%2Fsheerluxe%2Ffiles%2Farticles%2F2024%2F11%2Fsl-commercial-191124-therapie-1-v5.png?itok=qN-FabEa)

 

 ](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle) 

 

 

 

 

 

 

 [ ![](https://media.sheerluxe.com/hLi0zcYrPJ0oOj662oyL4ETZD4M=/1920x0/smart/filters:no_upscale()/https%3A%2F%2Fsheerluxe.com%2Fsites%2Fsheerluxe%2Ffiles%2Farticles%2F2024%2F11%2Fsl-commercial-191124-therapie-3-v7.png?itok=dabKNvcM)

 

 ](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle) 

 

 

 

 

 

 

 

## Who It's For 



  

“The best candidates are those who want to boost their collagen production – especially if they already have signs of ageing and crepey skin. Those with dark circles will really notice a difference too. Because the treatment stimulates collagen, ideal candidates are also those who want to improve skin’s texture, boost plumpness and reduce the appearance of scars. It’s a great option for those looking to minimise pigmentation too, as it stabilises the melanocytes within the skin – the cells which produce pigment.”

 

## What To Expect 



  

“Following a consultation with your chosen practitioner – where you’ll discuss skin health goals and what you want from the treatment – a numbing cream will be applied to the areas which will be injected, then a fine needle or cannula is used to inject the product into the skin. The most you will feel is a very light pressure from the needles going into your skin. The numbing cream is then removed, and the treatment begins. It takes around 20-35 minutes maximum, depending on how many injection sites there are. After that, you’re good to go – there is little downtime aside from some redness and potentially light bruising.”

 

## The Aftercare 



  

“I recommend having a course of three to four sessions, with two spaced two to four weeks apart. A maintenance session of one treatment every six months is also advised. These top-up appointments will optimise the process around your skin’s regeneration and allow it sufficient time to respond to injections. Skin cells need time to undergo turnover and regeneration. Polynucleotides can help to stimulate this process, but it won’t happen overnight. Patients often see improvement three weeks after their first treatment, as this is how long collagen synthesis takes – but the improvements will continue over the following two to three months.”

 

 

 

 [ ![](https://media.sheerluxe.com/w4GsgTaUAQC50xDSR4VPRP3JZpw=/800x0/smart/https%3A%2F%2Fsheerluxe.com%2Fsites%2Fsheerluxe%2Ffiles%2Farticles%2F2024%2F11%2Fsl-commercial-191124-therapie-4-v5.png?itok=Fgp-vM0g)

 

 ](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle) 

 

 

 

 

 

## The Risks &amp; Side Effects 



  

“As with any cosmetic procedure, Polynucleotides come with potential side effects, the most common being temporary bruising, redness or swelling. Overall, the treatment is deemed safe and compatible for most. My post-treatment advice is to avoid exercise, make-up and hot showers for at least 24 hours to keep irritation to a minimum. I also recommend not applying products until the next day to reduce risk of infection.”

 

## The Key Takeaways 



  

“The focus in the world of aesthetics is shifting to prevention and regeneration, which is where Polynucleotides come in. Previously, we’ve focused on treating the signs and symptoms of ageing with treatments like dermal fillers, but now we can also prevent these visible symptoms by treating the cause of the problem – which is often low collagen and elastin. Natural looking and beneficial for long-term prevention, Polynucleotides are a great alternative to other options out there. My final piece of advice is to always seek out medically qualified professionals for treatments like this. Always book a consultation and seek out doctor-led locations like [Thérapie](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle) Clinic to ensure the best and safest results.”

 

## Where To Book 



  

Thérapie Clinic has more than 76 locations across the UK, NYC and Ireland, and is Europe’s most in-demand medical aesthetic clinic, which makes it a no-brainer for treatments like Polynucleotides. It’s doctor led, with over 200 healthcare professionals available, so you know you’re in safe hands. Better still, this Black Friday, Thérapie Clinic are reducing the cost to £199 per session (normally £285.)\* The offer runs from November 18th for a limited time only.

*Vist* [THERAPIECLINIC.COM](https://therapieclinic.com/injectables/cosmetic-injections/polynucleotides?utm_source=sheerluxeBF&utm_medium=sheerluxeBFarticle)

\*When purchased as a course of three.

 

 

 

 

  

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